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Mechanism of vascular endothelial growth factor on the prevention of restenosis after angioplasty

Qigong LIU, Honglian ZHOU, Yan ZENG, Shan YE, Jiani LIU, Zaiying LU

Frontiers of Medicine 2009, Volume 3, Issue 2,   Pages 177-180 doi: 10.1007/s11684-009-0021-x

Abstract: To evaluate the mechanism of vascular endothelial growth factor (VEGF) on the prevention of restenosisangioplasty, the recombinant adenovirus vector containing hVEGF cDNA was constructed and transfected into vascular

Keywords： vascular endothelial growth factors     restenosis     reactive oxygen species     endothelial cells     vascular smoothmuscle cell    

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sulfate promotes the formation of atherosclerotic lesions and induces plaque instability by targeting vascular

Hui Han,Yanjia Chen,Zhengbin Zhu,Xiuxiu Su,Jingwei Ni,Run Du,Ruiyan Zhang,Wei Jin

Frontiers of Medicine 2016, Volume 10, Issue 3,   Pages 320-329 doi: 10.1007/s11684-016-0463-x

Abstract: Rat aortic vascular smooth muscle cells (VSMCs) were treated with phosphate buffer solution or 500 µ

Keywords： p-cresyl sulfate     atherosclerosis     plaque stability     vascular smooth muscle cell    

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Emerging roles of podoplanin in vascular development and homeostasis

Yanfang Pan,Lijun Xia

Frontiers of Medicine 2015, Volume 9, Issue 4,   Pages 421-430 doi: 10.1007/s11684-015-0424-9

Abstract:

Podoplanin (PDPN) is a mucin-type O-glycoprotein expressed in diverse cell types, suchas lymphatic endothelial cells (LECs) in the vascular system and fibroblastic reticular cells (FRCs)In the vascular system, normal expression of PDPN at the LEC surface requires transcriptional activationThis review provides a comprehensive overview of the roles of PDPN in vascular development and lymphoid

Keywords： podoplanin     CLEC-2     Prox1     O-glycosylation     lymphatic vascular development and maintenance     lymphoid    

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Buxu Tongyu Granule Alleviates Myocardial Ischemia by Activating Vascular Smooth Muscle Cell Soluble

Shuang Yang,Yixiu Zhao,Xiaoling Cheng,Tingting Zhan,Jiaying Tian,Xue Liu,Chunyue Ma,Zhiqi Wang,Luying Jin,Qian Liu,Yanli Wang,Jian Huang,Jinhui Wang,Yan Zhang,Baofeng Yang,

Engineering doi: 10.1016/j.eng.2023.06.009

Abstract: Myocardial ischemia is a serious threat to human health, and vascular dysfunction is its main cause.cyclase (sGC)–3′,5′-cyclic guanosine monophosphate (cGMP)–protein kinase G (PKG) signaling pathway in vascularThese effects were eliminated by pre-incubating vascular rings with the sGC inhibitors NS 2028 or ODQthe protein expression of sGC-β1 and the intracellular second messenger cGMP level in mouse aortic vascular

Keywords： Myocardial ischemia     Vasomotion     Soluble guanylate cyclase     Buxu Tongyu Granule    

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Crk-associated substrate, vascular smooth muscle and hypertension

TANG Dale

Frontiers of Medicine 2008, Volume 2, Issue 4,   Pages 323-331 doi: 10.1007/s11684-008-0062-6

Abstract: Hypertension is characterized by vascular smooth muscle constriction and vascular remodeling involvingcell migration, hypertrophy and growth.Evidence for the role of CAS in the regulation of vascular smooth muscle contractility is presented.The functions of CAS in cell migration, hypertrophy and growth are also summarized.The downstream signaling partners of CAS in the context of cell motility, hypertrophy, survival and growth

Keywords： Contraction stimulation     phosphatase-proline     molecular structure     discovered     hypertension    

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Role of nitric oxide in biological effects of vascular endothelial growth factor

Qigong LIU M D , Yan ZENG , Jiani LIU , Shan YE , Yongdong LI , Zaiying LU M D ,

Frontiers of Medicine 2009, Volume 3, Issue 3,   Pages 284-286 doi: 10.1007/s11684-009-0062-1

Abstract: To evaluate the role of nitric oxide in the biological effects of vascular endothelial growth factor(VEGF) and the possible mechanism of VEGF, the cultured vascular endothelial cells of rabbit aorta wereThe absorbance () value of vascular endothelial cells and the levels of prostaglandin (PGI), endothelinVEGF could promote the proliferation and secretion of PGI and inhibit the secretion of ET-1 and vWF in vascularoxide is an important mediator in the process of stimulating proliferation and regulating secretion of vascular

Keywords： vascular endothelial growth factor     nitric oxide     N-nitro-L-arginine methyl ester     vascular endothelial    

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Progress in tumor vascular normalization for anticancer therapy: challenges and perspectives

Bingxue Shang, Zhifei Cao, Quansheng Zhou

Frontiers of Medicine 2012, Volume 6, Issue 1,   Pages 67-78 doi: 10.1007/s11684-012-0176-8

Abstract: In 2001, Jain proposed tumor vascular normalization as an alternative approach to treating cancers basedPreclinical and clinical data have shown that tumor vascular normalization using monoclonal antibodiesHowever, current tumor vascular normalizing drugs display moderate anticancer efficacy.Therefore, multiple-targeting of vasculogenic tumor cells and genes may improve the efficacy of tumor vascularTo this end, the combination of antiangiogenic drugs with tumor vascular normalizing therapeutics, as

Keywords： angiogenesis     vasculogenesis     neovascularization     tumor     vasculature     normalization     traditional Chinese medicine    

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Endogenous tissue factor pathway inhibitor in vascular smooth muscle cells inhibits arterial thrombosis

Jichun Yang, Kaiyue Jin, Jiajun Xiao, Jing Ma, Duan Ma

Frontiers of Medicine 2017, Volume 11, Issue 3,   Pages 403-409 doi: 10.1007/s11684-017-0522-y

Abstract: However, the role of endogenous TFPI in vascular smooth muscle cells (VSMCs) in thrombosis and vascular

Keywords： arterial thrombosis     conditional knockout mice     tissue factor pathway inhibitor     vascular smooth muscle    

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Alteration of heat shock protein 20 expression in preeclamptic patients and its effect in vascular and

Fanfan Li, Mengzhou He, Meitao Yang, Yao Fan, Yun Chen, Xi Xia, Yin Xie, Dongrui Deng

Frontiers of Medicine 2018, Volume 12, Issue 5,   Pages 542-549 doi: 10.1007/s11684-017-0576-x

Abstract: (HSP20) is ubiquitously expressed under normal physiological conditions and has important roles in vascular

Keywords： preeclampsia     heat shock protein 20     vascular relaxation     coagulation-fibrinolytic system    

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Visualization of vascular ultrastructure during osteogenesis by tissue engineering technique

ZHANG Kaigang, ZENG Bingfang, ZHANG Changqing

Frontiers of Medicine 2007, Volume 1, Issue 2,   Pages 181-184 doi: 10.1007/s11684-007-0034-2

Abstract: The aim of this paper was to observe and visualize the changes in osteoblasts by electron microscopy during osteogenesis using tissue engineering technique. We also studied the feasibility of improving tissue vascularization of th

Keywords： feasibility     engineering     osteogenesis     vascularization     microscopy    

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Effect of bradykinin on bradykinin-B2 receptor in rat aortic vascular smooth muscle cells and the involved

Wen YAN MD, Min FENG MD, Pei-Hua WANG MD, Dao-Wen WANG MD,

Frontiers of Medicine 2010, Volume 4, Issue 2,   Pages 225-228 doi: 10.1007/s11684-010-0003-z

Abstract: bradykinin-B2 receptor as well as the possible involved signal transduction pathways in cultured rat aortic vascular

Keywords： bradykinin     vascular smooth muscle cells     signal transduction pathways    

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The second short-term warm ischemia after vascular anastomosis did not affect early renal function recovery

Tao Qiu, Jiangqiao Zhou, Xiuheng Liu, Minghuan Ge, Zhiyuan Chen

Frontiers of Medicine 2012, Volume 6, Issue 3,   Pages 329-331 doi: 10.1007/s11684-012-0211-9

Abstract:

Ischemic postconditioning was defined as rapid intermittent interruptions of blood ?ow in the early phase of reperfusion, which has been found to be protective against renal ischemia-reperfusion injury (IRI) in animal models but not in clinical trials. We describe a case that the allograft renal vein was twisted because of the surgeon’s mistake, which caused the warm ischemia of allograft after reperfusion. The allograft restored blood flow without second reperfusion and cold preservation after 9 min of warm ischemia. The patient was followed up for 3 months and the allograft worked well without complications.

Keywords： renal transplantation     vein twist     ischemia-reperfusion injury    

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Stroke prevention: an update

Marie-Germaine Bousser

Frontiers of Medicine 2012, Volume 6, Issue 1,   Pages 22-34 doi: 10.1007/s11684-012-0178-6

Abstract: of stroke is likely to increase given the aging of the population and the growing incidence of many vascularThe mass approach is primarily based on the identification and treatment of vascular risk factors andThe individual approach combines a vascular risk factor modification and various treatments addressing

Keywords： stroke     prevention     vascular risk factors     cerebral infarction     cerebral hemorrhage     anti-thrombotic drugs    

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Beneficial effect of arginine vasopressin on hemorrhagic shock through improving the vascular reactivity

LI Tao, YANG Guangming, XU Jing, LIU Jiancang, LIU Liangming

Frontiers of Medicine 2008, Volume 2, Issue 3,   Pages 248-254 doi: 10.1007/s11684-008-0047-5

Abstract: The vascular reactivity and calcium sensitivity were decreased following hemorrhagic shock.have beneficial effect on shock via activation of Rho kinase to regulate the calcium sensitivity and vascularIsolated SMAs from hemorrhagic shock rats were adopted to observe the effects of AVP on vascular reactivityRho kinase specific inhibitor, abolished the beneficial effects of AVP. , the calcium sensitivity and vascularat the concentration of 0.5 nmol/L and 5 nmol/L significantly increased the calcium sensitivity and vascular
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Lymphatic metastasis is related to the epithelial-mesenchymal transition and expressions of VEGF, MMP-9, and COX-2 in breast cancer

Lihui WANG, Lianhong LI, Shen LV, Shujun FAN, Li ZHAN, Bo WANG, Zhong ZHANG

Frontiers of Medicine 2009, Volume 3, Issue 2,   Pages 164-170 doi: 10.1007/s11684-009-0038-1

Abstract: The expressions of E-cadherin (E-Cad), N-cadherin (N-Cad), vascular endothelial cell growth factor (VEGF

Keywords： epithelial-mesenchymal transition     vascular endothelial cell growth factor     matrix metalloproteinase-9    

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Title Author Date Type Operation

Mechanism of vascular endothelial growth factor on the prevention of restenosis after angioplasty

Qigong LIU, Honglian ZHOU, Yan ZENG, Shan YE, Jiani LIU, Zaiying LU

Journal Article

sulfate promotes the formation of atherosclerotic lesions and induces plaque instability by targeting vascular

Hui Han,Yanjia Chen,Zhengbin Zhu,Xiuxiu Su,Jingwei Ni,Run Du,Ruiyan Zhang,Wei Jin

Journal Article

Emerging roles of podoplanin in vascular development and homeostasis

Yanfang Pan,Lijun Xia

Journal Article

Buxu Tongyu Granule Alleviates Myocardial Ischemia by Activating Vascular Smooth Muscle Cell Soluble

Shuang Yang,Yixiu Zhao,Xiaoling Cheng,Tingting Zhan,Jiaying Tian,Xue Liu,Chunyue Ma,Zhiqi Wang,Luying Jin,Qian Liu,Yanli Wang,Jian Huang,Jinhui Wang,Yan Zhang,Baofeng Yang,

Journal Article

Crk-associated substrate, vascular smooth muscle and hypertension

TANG Dale

Journal Article

Role of nitric oxide in biological effects of vascular endothelial growth factor

Qigong LIU M D , Yan ZENG , Jiani LIU , Shan YE , Yongdong LI , Zaiying LU M D ,

Journal Article

Progress in tumor vascular normalization for anticancer therapy: challenges and perspectives

Bingxue Shang, Zhifei Cao, Quansheng Zhou

Journal Article

Endogenous tissue factor pathway inhibitor in vascular smooth muscle cells inhibits arterial thrombosis

Jichun Yang, Kaiyue Jin, Jiajun Xiao, Jing Ma, Duan Ma

Journal Article

Alteration of heat shock protein 20 expression in preeclamptic patients and its effect in vascular and

Fanfan Li, Mengzhou He, Meitao Yang, Yao Fan, Yun Chen, Xi Xia, Yin Xie, Dongrui Deng

Journal Article

Visualization of vascular ultrastructure during osteogenesis by tissue engineering technique

ZHANG Kaigang, ZENG Bingfang, ZHANG Changqing

Journal Article

Effect of bradykinin on bradykinin-B2 receptor in rat aortic vascular smooth muscle cells and the involved

Wen YAN MD, Min FENG MD, Pei-Hua WANG MD, Dao-Wen WANG MD,

Journal Article

The second short-term warm ischemia after vascular anastomosis did not affect early renal function recovery

Tao Qiu, Jiangqiao Zhou, Xiuheng Liu, Minghuan Ge, Zhiyuan Chen

Journal Article

Stroke prevention: an update

Marie-Germaine Bousser

Journal Article

Beneficial effect of arginine vasopressin on hemorrhagic shock through improving the vascular reactivity

LI Tao, YANG Guangming, XU Jing, LIU Jiancang, LIU Liangming

Journal Article

Lymphatic metastasis is related to the epithelial-mesenchymal transition and expressions of VEGF, MMP-9, and COX-2 in breast cancer

Lihui WANG, Lianhong LI, Shen LV, Shujun FAN, Li ZHAN, Bo WANG, Zhong ZHANG

Journal Article